Fluorescent metal-based complexes as cancer probes |
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Affiliation: | 1. Tumour Microenvironment Group, Division of Cancer and Genetics School of Medicine, Cardiff University, Tenovus Building, Cardiff CF14 4XN, UK;2. School of Chemistry, Cardiff University Park Place, CF10 3AT Cardiff, UK;1. Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science & Technology Normal University, Nanchang, 330013, PR China;2. Department of Ecology and environment, Yuzhang Normal University, Nanchang, 330103, PR China |
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Abstract: | The ability to track drugs inside of cells and tumours has been highly valuable in cancer research and diagnosis. Metal complexes add attractive features to fluorescent drugs, such as targeting and specificity, solubility and uptake or photophysical properties. This review focuses on the latest fluorescent metal-based complexes, their cellular targets, photophysical properties and possible anticancer effects. |
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Keywords: | Fluorescent probes Metal complexes Theranostics Targeting Metal-based probes Anticancer probes Fluorescence microscopy |
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