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Ultrastructural Studies on Bovine Horn Cancer
Authors:Somuanshi  Ramesh  Mukherjee  Subhas C  Rehbinder  Claes
Institution:1.Division of Pathology, Indian Veterinary Research Institute, Izatnagar, India and the Department of Pathology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, S-750 07, Uppsala, Sweden
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Abstract:The ultrastructure of bovine horn cancer (squamous cell carcinoma) of Indian cattle is described. The tumour was composed of pleomorphic epithelial cells. The nuclei were enlarged with membrane invaginations and peripherally distributed heterochromatin and pleomorphic nucleoli. The cytoplasm contained bundles of tono-filaments and keratohyalin granules. In addition a majority of the cells revealed marked degenerative changes of the cytoplasmic orga-nellae and intracellular oedema. Desmosomes were rarely observed. Budding of virus-like particles from the cell membrane of a few cells was demonstrated.
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