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Pre-emptive Quality Control of a Misfolded Membrane Protein by Ribosome-Driven Effects
Institution:1. Department of Biological Sciences, Columbia University, 1212 Amsterdam Ave., New York, NY 10027, USA;2. Medical Research Council Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Ave., Cambridge CB2 0QH, UK;3. Cambridge Institute for Medical Research, The Keith Peters Building, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK;4. Department of Haematology, The Keith Peters Building, University of Cambridge, Hills Road, Cambridge CB2 0XY, UK;5. Wellcome Trust – Medical Research Council Stem Cell Institute, University of Cambridge, Puddicomb Way, Cambridge CB2 0AW, UK
Abstract:
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  • Keywords:protein quality control  ribosome-associated quality control  protein folding  endoplasmic reticulum  translational tuning
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