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On the topological evidences for modelling lipophilicity |
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| Authors: | Agrawal Vijay K Singh Jyoti Khadikar Padmakar V |
| Affiliation: | a QSAR and Chemical Laboratories, A.P.S. University, Rewa-486 003, India b Research Division, Laxmi Fumigation and Pest Control Pvt. Ltd. 3, Khatipura, Indore-452 007, India |
| Abstract: | Topological evidences for modelling lipophilicity of a large series of diversed compounds have been provided on the basis of distance-based topological indices. A pool of topological indices along with indicator parameters related to the type of the compounds present in the set of 140 compounds were used for this purpose. The results have shown that topology as well as the type of compounds are the responsible parameters for modelling lipophilicity. |
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