Immunoglobulin biosynthesis. V. Light chain assembly |
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Authors: | D Schubert M Cohn |
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Affiliation: | The Salk Institute for Biological Studies San Diego, Calif., U.S.A. |
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Abstract: | A protein one-half the size of and antigenically related to light chain was found in immunoglobulin and light chain producing myelomas. The kinetics of its turnover are not consistent with its being a degradation product of light chain. The possibility that this immunoglobulin fragment is a synthetic intermediate in light chain biosynthesis is analyzed and discussed in the context of other data on light chain biosynthesis. |
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