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Development of the Minimum Information Specification for In Situ Hybridization and Immunohistochemistry Experiments (MISFISHIE)
Authors:Deutsch Eric W  Ball Catherine A  Bova G Steven  Brazma Alvis  Bumgarner Roger E  Campbell David  Causton Helen C  Christiansen Jeff  Davidson Duncan  Eichner Lillian J  Goo Young Ah  Grimmond Sean  Henrich Thorsten  Johnson Michael H  Korb Martin  Mills Jason C  Oudes Asa  Parkinson Helen E  Pascal Laura E  Quackenbush John  Ramialison Mirana  Ringwald Martin  Sansone Susanna-A  Sherlock Gavin  Stoeckert Christian J  Swedlow Jason  Taylor Ronald C  Walashek Laura  Zhou Yi  Liu Alvin Y  True Lawrence D
Institution:Institute for Systems Biology, Seattle, Washington 98103, USA. edeutsch@systemsbiology.org
Abstract:We describe the creation process of the Minimum Information Specification for In Situ Hybridization and Immunohistochemistry Experiments (MISFISHIE). Modeled after the existing minimum information specification for microarray data, we created a new specification for gene expression localization experiments, initially to facilitate data sharing within a consortium. After successful use within the consortium, the specification was circulated to members of the wider biomedical research community for comment and refinement. After a period of acquiring many new suggested requirements, it was necessary to enter a final phase of excluding those requirements that were deemed inappropriate as a minimum requirement for all experiments. The full specification will soon be published as a version 1.0 proposal to the community, upon which a more full discussion must take place so that the final specification may be achieved with the involvement of the whole community.
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