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Adenoviral overexpression of Lhx2 attenuates cell viability but does not preserve the stem cell like phenotype of hepatic stellate cells
Authors:Berit Genz  Maria Thomas  Brigitte M Pützer  Marcin Siatkowski  Georg Fuellen  Brigitte Vollmar  Kerstin Abshagen
Institution:1. Institute for Experimental Surgery, Rostock University Medical Center, Rostock, Germany;2. Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany;3. Institute of Experimental Gene Therapy and Cancer Research, Rostock University Medical Center, Rostock, Germany;4. Institute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock University Medical Center, Rostock, Germany
Abstract:
Keywords:αSMA  alpha smooth muscle actin  ECM  extracellular matrix  eGFP  enhanced green fluorescence protein  HSC  hepatic stellate cells  Lhx2  LIM homeobox protein 2  PDGF  platelet derived growth factor  p  i    post infection  Sox9  sex determining region Y-box 9  TGF-β  transforming growth factor beta
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