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Two wheat decapeptides prevent gliadin-dependent maturation of human dendritic cells
Authors:Luciana Giordani  Tamara Del Pinto  Olimpia Vincentini  Cristina Felli  Marco Silano  Marina Viora
Institution:1. Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy;2. Department of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Viale Regina Elena, 299, 00161 Rome, Italy
Abstract:Celiac disease (CD) is a small intestinal enteropathy, triggered in susceptible individuals by the ingestion of dietary gluten.
Keywords:CD  celiac disease  DC  dendritic cells  iDC  immature dendritic cells  PT-gliadin  peptic-tryptic digest of gliadin  HLA  PBMC  peripheral blood mononuclear cells  human leukocyte antigen  IL  interleukin  APC  antigen presenting cells  LPS  lipopolysaccharide  mAbs  monoclonal antibodies  MLR  mixed lymphocyte reaction
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