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Altered epigenetic regulation of homeobox genes in human oral squamous cell carcinoma cells

Authors:	Katarzyna M Marcinkiewicz Lorraine J Gudas

Institution:	Department of Pharmacology, Weill Cornell Medical College of Cornell University, 1300 York Avenue, New York, NY 10065, USA; Department of Pharmacology, Weill Cornell Graduate School of Medical Sciences of Cornell University, 1300 York Avenue, New York, NY 10065, USA

Abstract:

Keywords:	ChIP chromatin immunoprecipitation GAPDH glyceraldehyde 3-phosphate dehydrogenase GO gene ontology H3K27me3 histone 3 lysine 27 trimethyl HNSCC head and neck squamous cell carcinoma HOX homeobox HPRT1 hypoxanthine phosphoribosyltransferase 1 OSCC oral squamous cell carcinoma PRC polycomb repressive complexes qRT-PCR quantitative real time polymerase chain reaction RA retinoic acid RAR retinoic acid receptor RARE retinoic acid response element RNAseq RNA sequencing RXR retinoid X receptor shRNA short hairpin RNA SCC squamous cell carcinoma TNM TNM classification of malignant tumours WCMC Weill Cornell Medical College
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