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BRCA1 is a negative modulator of the PRC2 complex
Authors:Liya Ding  Jian Zhong  Jonathan C Zhao  Liguo Wang  Aaron Sarver  Antonius Koller  Jizu Zhi  Yupo Ma  Jindan Yu  Junjie Chen  Haojie Huang
Institution:1. Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, , Rochester, MN, USA;2. Mayo Clinic Cancer Center, Mayo Clinic College of Medicine, , Rochester, MN, USA;3. Divison of Hematology/Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, , Chicago, IL, USA;4. Department of Biomedical Statistics and Informatics, Mayo Clinic College of Medicine, , Rochester, MN, USA;5. Masonic Cancer Center, University of Minnesota, , Minneapolis, MN, USA;6. Department of Pathology, Stony Brook University Medical Center, , Stony Brook, NY, USA;7. Department of Experimental Radiation Oncology, University of Texas M. D. Anderson Cancer Center, , Houston, TX, USA
Abstract:
Keywords:BRCA1  breast cancer  embryonic stem cell  epigenetic gene silencing  PRC2
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