Effect of ATP and Bax on the apoptosis of <Emphasis Type="Italic">Eimeria tenella</Emphasis> host cells期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Effect of ATP and Bax on the apoptosis of Eimeria tenella host cells

Authors:	Zhiyong Xu Mingxue Zheng Li Zhang Xuesong Zhang Yan Zhang Xiaozhen Cui Xin Gong Rou Xi Rui Bai

Affiliation:	1.College of Animal Science and Technology,Shanxi Agricultural University,Taigu,China;2.College of Animal Science and Technology,Henan Institute of Science and Technology,Xinxiang,China

Abstract:	Background Eimeria tenella (E. tenella) is a species of Eimeria that causes haemorrhagic caecal coccidiosis, resulting in major economic losses in the global poultry industry. After E. tenella infection, the amount of ATP and Bax in host cells showed highly significant changes. Therefore, it is necessary to investigate the effects of ATP and Bax on the apoptosis of E. tenella host cells. Results The ATP-treated group and the V5-treated group had higher E. tenella infection rates than the untreated group at 24, 48, 72, 96, and 120 h after infection with E. tenella. The results of flow cytometry showed that compared with the control group, the mitochondrial permeability transition pore (MPTP) opening in the untreated group was highly significantly increased (P?P?P?P?P?P?P? Conclusions ATP and Bax play important roles in regulating the apoptosis of E. tenella host cells.

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