Imaging extracellular vesicles: current and emerging methods |
| |
Authors: | Steven Ting-Yu Chuo Jasper Che-Yung Chien Charles Pin-Kuang Lai |
| |
Affiliation: | 1.Institute of Atomic and Molecular Sciences,Academia Sinica,Taipei,Taiwan;2.Chemical Biology and Molecular Biophysics Program, Taiwan International Graduate Program,Academia Sinica,Taipei,Taiwan;3.Genome and Systems Biology Degree Program,National Taiwan University and Academia Sinica,Taipei,Taiwan |
| |
Abstract: | Extracellular vesicles (EVs) are lipid bilayer-enclosed nanoparticles released by cells. They range from 30?nm to several micrometers in diameter, and ferry biological cargos such as proteins, lipids, RNAs and DNAs for local and distant intercellular communications. EVs have since been found to play a role in development, as well as in diseases including cancers. To elucidate the roles of EVs, researchers have established different methods to visualize and study their spatiotemporal properties. However, since EV are nanometer-sized, imaging them demands a full understanding of each labeling strategy to ensure accurate monitoring. This review covers current and emerging strategies for EV imaging for prospective studies. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|