| 柠檬醛胁迫环境下黄曲霉线粒体的畸变 |
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| 引用本文： | 罗曼 蒋立科 戴向荣. 柠檬醛胁迫环境下黄曲霉线粒体的畸变[J]. 微生物学报, 2006, 46(6): 1011-1013 |
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| 作者姓名： | 罗曼 蒋立科 戴向荣 |
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| 作者单位： | 1. 暨南大学生物医学工程研究所,广州,510632
2. 安徽农业大学生命科学学院,合肥,230036 |
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| 基金项目： | 国家发改委、农业部中试联合项目 |
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| 摘 要： | 通过对黄曲霉细胞受柠檬醛损伤后线粒体形态畸变的透射电镜观察,发现柠檬醛所产生胁迫环境影响线粒体DNA复制系统,产生增生变异的巨型线粒体而与之应答。丙二醛法测定黄曲霉细胞内自由基,结果表明药物进入细胞后还通过诱发自由基使线粒体损伤,致使氧化还原系统及细胞能量代谢途径受到影响。
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| 关 键 词： | 柠檬醛 黄曲霉 线粒体畸变 |
| 文章编号： | 0001-6209（2006）06-1011-03 |
| 收稿时间： | 2006-02-27 |
| 修稿时间： | 2006-05-11 |
Mitochondria aberration of Aspergillus flavus under citral stress circumstance |
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| LUO Man,JIANG Li-ke,DAI Xiang-rong. Mitochondria aberration of Aspergillus flavus under citral stress circumstance[J]. Acta microbiologica Sinica, 2006, 46(6): 1011-1013 |
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| Authors: | LUO Man JIANG Li-ke DAI Xiang-rong |
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| Affiliation: | 1 Institute of Biomedical Engineering, Jinan University, Guangzhou 510632, China ;2 College of Life Sciences, Anhui Agricultural University, Hefei 230036, China |
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| Abstract: | Observation of mitochondrion in Aspergillus flavus damaged by citral under uransmission electron microscope, it was found that mitochondria had changes on number increase and shape aberrance as hyperplasia or hypertrophy, which resulted from the DNA replication system in mitochondria was damaged by citral. From the data that free radical in A. flavus which were determined by MDA method, it was showed that citral damaged mitochondria via induced free radical, which affected oxidation-reduction system and energy metabolism. |
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| Keywords: | Citral Aspergillus flavus Mitochondria aberrance |
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