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Synthesis and antitumor activity of novel paclitaxel-chlorambucil hybrids |
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| Authors: | Wittman M D Kadow J F Vyas D M Lee F L Rose W C Long B H Fairchild C Johnston K |
| Affiliation: | Discovery Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, CT 06492-7660, USA. mark.wittman@bms.com |
| Abstract: | The syntheses and antitumor activity of three paclitaxel-chlorambucil hybrids are presented. Hybrid 3 showed significant in vivo efficacy. |
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