Signet-ring cell lymphoma. Report of a case diagnosed by fine needle aspiration cytology |
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| Authors: | J M Limjoco J J Brooks J B Alavi |
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| Institution: | Department of Pathology, University of Pennsylvania Medical School, Philadelphia. |
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| Abstract: | A case of signet-ring cell lymphoma initially diagnosed by fine needle aspiration (FNA) cytology is described. Immediate evaluation of air-dried smears showed a mixture of large and small lymphoid cells, including some signet-ring forms. Immunocytochemical studies of Cytospin preparations of the remaining aspirate yielded a diagnosis of a large-cell-type B-cell signet-ring lymphoma. Subsequent bone marrow biopsies confirmed the diagnosis of a low-grade lymphoma. The advantages of on-site evaluation in aspiration cytology are discussed. |
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