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Synthesis of the novel analogues of dysidiolide and their structure-activity relationship
Authors:Takahashi M  Dodo K  Sugimoto Y  Aoyagi Y  Yamada Y  Hashimoto Y  Shirai R
Affiliation:Institute of Molecular and Cellular Biosciences, The University of Tokyo, Japan.
Abstract:The novel analogues of natural cdc25A inhibitor dysidiolide were synthesized. To investigate the structure-activity relationship, the inhibitory activity to enzyme and cell cycle was examined.
Keywords:
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