| 氨基酸转运载体研究进展 |
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| 引用本文： | 何庆华,孔祥峰,吴永宁,印遇龙.氨基酸转运载体研究进展[J].氨基酸和生物资源,2007,29(2):42-45,58. |
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| 作者姓名： | 何庆华 孔祥峰 吴永宁 印遇龙 |
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| 作者单位： | 中国科学院亚热带农业生态研究所动物生态营养与健康养殖联合实验室,长沙,410125;中国科学院研究生院,北京,100049;中国科学院亚热带农业生态研究所动物生态营养与健康养殖联合实验室,长沙,410125;中国疾病预防控制中心营养与食品安全所,北京,100050 |
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| 基金项目： | 中国科学院知识创新工程重要方向项目(Kscx2-Yw-N-022KSCX2-SW-323)，国家973项目(2004CB117502)，国家自然科学基金项目(30528006) |
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| 摘 要： | 氨基酸转运载体是介导氨基酸跨膜转运的膜蛋白,在氨基酸营养机体细胞和神经调节过程中起着重要作用;而且,其功能异常会导致严重的氨基酸吸收和代谢障碍性疾病,也具有重要的病理学意义。本文就近年来关于中性氨基酸、酸性氨基酸和碱性氨基酸转运载体家族成员及其组织分布、分子生物学特征、生理功能和病理学意义等研究进展进行了综述。
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| 关 键 词： | 氨基酸转运载体 中性氨基酸 酸性氨基酸 碱性氨基酸 |
| 文章编号： | 1006-8376（2007）02-0042-04 |
| 修稿时间： | 2007-03-16 |
Research Progress on Amino Acid Transporters |
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| HE Qing-hua,KONG Xiang-feng,WU Yong-ning,YIN Yu-long.Research Progress on Amino Acid Transporters[J].Amino Acids & Biotic Resources,2007,29(2):42-45,58. |
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| Authors: | HE Qing-hua KONG Xiang-feng WU Yong-ning YIN Yu-long |
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| Institution: | 1. Laboratory of Animal Nutrition and Human Health and Key Laboratory of Subtropical Agro - ecology, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China ; 2. National Institute for Nutrition and Food Safety, Chinese CDC, Beijing 100050, China; 3. Graduate School of the Chinese Academy of Sciences, Beijing 100049, China |
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| Abstract: | Amino acid transporters are the membrane proteins which mediate the transport of amino acids across the plasma membrane.They are required not only to supply cells with amino acids for cellular nutrition but also to fulfill specialized cellular functions.Their functional abnormity can induce the severe disorder of amino acids absorbability and metabolism.This article mainly discussed members of neutral,acidic and basic amino acid transporters and their tissue distribution,biological characteristics and physiological and pathological roles. |
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| Keywords: | amino acid transporters neutral amino acid acidic amino acid basic amino acid |
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