首页 | 本学科首页   官方微博 | 高级检索  
   检索      


Cladocalol, a pentacyclic 28-nor-triterpene from Eucalyptus cladocalyx with cytotoxic activity
Authors:Benyahia Samira  Benayache Samir  Benayache Fadila  León Francisco  Quintana José  López Matías  Hernández Juan C  Estévez Francisco  Bermejo Jaime
Institution:Laboratory of Valorisation of Natural Resources, University of Constantine, Constantine 25000, Algeria.
Abstract:A formylated triterpene named cladocalol has been isolated from the leaves of Eucalyptus cladocalyx, together with ursulolactone acetate, ursolic acid, 3 beta-acetate-12,20(29)-lupadien-28-oic acid, beta-sitosterol and the known flavonoid eucalyptine. Their structures were mainly established by extensive NMR studies (1H NMR, 13C NMR, DEPT, 1H-1H COSY, HSQC, HMBC) and mass spectroscopy as well as by X-ray crystallographic analysis. In this paper, we report on the cytotoxic effect induced by cladocalol and its derivatives on the myeloid leukemia cell line HL-60.
Keywords:Eucalyptus cladocalyx  Myrtaceae  Pentacyclic triterpenes  Sterol  Flavonoid  Single-crystal X-ray analysis  Cytotoxic
本文献已被 ScienceDirect PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号