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Widespread Alterations in Translation Elongation in the Brain of Juvenile Fmr1 Knockout Mice
Authors:Sohani Das Sharma  Jordan B. Metz  Hongyu Li  Benjamin D. Hobson  Nicholas Hornstein  David Sulzer  Guomei Tang  Peter A. Sims
Affiliation:1. Department of Systems Biology, Columbia University Medical Center, New York, NY 10032, USA;2. Medical Scientist Training Program, Columbia University Medical Center, New York, NY 10032, USA;3. Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA;4. Department of Psychiatry, Columbia University Medical Center, New York, NY 10032, USA;5. Department of Pharmacology, Columbia University Medical Center, New York, NY 10032, USA;6. Division of Molecular Therapeutics, New York State Psychiatric Institute, New York, NY 10032, USA;7. Department of Biochemistry & Molecular Biophysics, Columbia University Medical Center, New York, NY 10032, USA;8. Sulzberger Columbia Genome Center, Columbia University Medical Center, New York, NY 10032, USA
Abstract:
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  • Keywords:fragile X syndrome  translational regulation  ribosome profiling
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