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Cytoskeletal Control of Antigen-Dependent T Cell Activation
Authors:Huw Colin-York  Yousef Javanmardi  Mark Skamrahl  Sudha Kumari  Veronica T. Chang  Satya Khuon  Aaron Taylor  Teng-Leong Chew  Eric Betzig  Emad Moeendarbary  Vincenzo Cerundolo  Christian Eggeling  Marco Fritzsche
Affiliation:1. MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Headley Way, Oxford OX3 9DS, UK;2. Department of Mechanical Engineering, University College London, London WC1E 7JE, UK;3. Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;4. MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK;5. Janelia Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA;6. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA;7. Kennedy Institute for Rheumatology, University of Oxford, Roosevelt Drive, Oxford OX3 7LF, UK
Abstract:
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  • Keywords:TFM  actin dynamics  TCR cluster  immunological synapse  mechanosensation  mechanosensitivity  T cell activation
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