Evolution of the lymphoid system. IV. Murine T-independent but not T-dependent antigens are very immunogenic in rainbow trout (Salmo gairdneri). |
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| Authors: | H M Etlinger J M Chiller H O Hodgins |
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| Affiliation: | 1. Department of Medicine, Section of Basic Immunology, National Jewish Hospital and Research Center, Denver, Colorado, USA;2. Environmental Conservation Division, Northwest and Alaska Fisheries Center, Seattle, Washington, USA |
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| Abstract: | Adult rainbow trout (RBT) were found to respond well to murine T-independent antigens but not to T-dependent antigens. In addition, the ability of RBT to respond with adult intensity to at least one murine T-independent antigen occurred very early in their ontogenetic development. Finally, subsequent to antigenic challenge, it was observed that while large numbers of plaque-forming cells appeared in the spleen and anterior kidney, none were found in the thymus. |
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