Estrone sulfate, estrone and estradiol concentrations in normal and cirrhotic postmenopausal women |
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Authors: | V M Jasonni C Bulletti G F Bolelli F Franceschetti M Bonavia P Ciotti C Flamigni |
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Institution: | Department of Reproductive Physiopathology, University of Bologna, St Orsola''s General Hospital, Massarenti Rd. 13, 40138 Bologna - Italy |
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Abstract: | Circulating levels (mean +/- SD) of estrone sulfate (E1S), estrone (E1) and estradiol-17 beta (E2) were measured in normal and cirrhotic postmenopausal women matched for body weight and age. In cirrhotic postmenopausal women, the E1S concentrations (201 +/- 46 pg/ml), while both E1 and E2 levels showed an increase (46 +/- 7 and 30 +/- 8 pg/ml) compared to control subjects (32 +/- 6 and 18 +/- 7 pg/ml). These data suggest that the liver plays an important role on the control of estrogen sulfation. |
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