The effect of doxycycline on the intestinal alkaline phosphatase (EC 3.1.3.1) activity in rat. A quantitative study |
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Authors: | I E Wi?niewska Z Gawlik |
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Affiliation: | Department of Pharmacodynamics, Academy of Medicine, Warszawa, Poland. |
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Abstract: | The doxycycline effect on the alkaline phosphatase activity in the small intestinal glandular epithelium in rat was examined, using the interferometric technique. The antibiotic caused a statistically significant fall of the alkaline phosphatase activity and the enzyme was found to decrease with consecutive doses of the drug. |
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