Plasmid-mediated virulence genes in non-typhoid Salmonella serovars |
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| Authors: | Donald G Guiney Ferric C Fang Martin Krause Stephen Libby |
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| Institution: | Department of Molecular and Cellular Biology, BioCentrum Amsterdam, Vrije Universiteit, De Boelelaan 1087, NL-1081 HV Amsterdam, the Netherlands; Lehrstuhl für Mikrobiologie, Universität Karlsruhe, Kaiserstrasse 12, D-76128 Karlsruhe, FRG |
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| Abstract: | Abstract Among aerobic prokaryotes, many different terminal oxidase complexes have been described. Sequence comparison has revealed that the aa 3-type cytochrome c oxidase and the bo 3-type quinol oxidase are variations on the same theme: the heme-copper oxidase. A third member of this family has recently been recognized: the cbb 3-type cytochrome c oxidase. Here we give an overview, and report that nitric oxide (NO) reductase, a bc -type cytochrome involved in denitrification, shares important features with these terminal oxidases as well. Tentative structural, functional and evolutionary implications are discussed. |
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| Keywords: | Respiration Cytochrome c oxidase Quinol oxidase Denitrification Nitric oxide reductase Nitrous oxide reductase |
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