(1) Wellcome Trust Sanger Institute, CB10 1SA, Hinxton, Cambridge, UK;(2) Institute of Molecular Biology, Center of Excellence for Molecular Medicine, Slovak Academy of Sciences, Dubravska cesta 21, 845 51 Bratislava, Slovak Republic
Abstract:
Background
Streptomyces coelicolor is a bacterium with a vast repertoire of metabolic functions and complex systems of cellular development. Its genome sequence
is rich in genes that encode regulatory proteins to control these processes in response to its changing environment. We wished
to apply a recently published bioinformatic method for identifying novel regulatory sequence signals to gain new insights
into regulation in S. coelicolor.