Chemical constituents of Brazilian Propolis from the state of Bahia and their growth inhibitory activities against cancer cells |
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| Authors: | Taichi Mitsui Sho Hotta Shigemi Tazawa Yasuko Arai Kenji Kato |
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| Affiliation: | Nagaragawa Research Center, Api Co. Ltd., Gifu, Japan |
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| Abstract: | A novel 2-phenoxychromone (1) and five known flavones (2-6) were isolated from northeastern Brazilian propolis in the state of Bahia. The chemical structures of these six compounds were determined by spectroscopic investigations and single-crystal X-ray analysis. The isolated compounds showed growth-inhibitory activities, in varying degrees, against human tumor cell lines. This is the first report on the discovery of a novel 2-phenoxychromone from propolis. |
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| Keywords: | Brazilian propolis Bahia state 2-Phenoxychromone anti-cancer |
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