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The indices of rat open-field behavior and the characteristics of the survival and functional recovery of the CNS following circulatory arrest
Authors:E A Mutuskina  N I Nezlina  M A Kulikov  A M Gurvich
Abstract:In experiments on rats it has been shown that for prognostication of successful reanimation after the clinic death of different duration (5, 10, 15 min) correlative interactions between the parameters of behaviour in the open field before blood circulation cessation are more essential than their absolute values. Highly significant correlation coefficients (0.7 and more) between the majority of behaviour parameters were typical for the group of animals which had survived after a prolonged blood circulation cessation (15 min); for rats rehabilitated after 5- and 10-min cessation of the blood circulation--between the characteristics reflecting, basically, the motor-investigating component of the behaviour. In groups of died animals (independently on the duration of clinic death) correlation profile was restricted to characteristics determining only the character of the motor activity. Particular significance is underlined of emotionally psychic components of the behaviour for complete CNS restoration after a prolonged blood circulation cessation in comparison with the shorter ones.
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