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Mutagenicity of bithionol sulfoxide and its metabolites in the salmonella/mammalian microsome test |
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| Authors: | D Mourot A Mourot |
| Abstract: | The mutagenic effects of bithionol sulfoxide and its two major metabolites, bithionol and bithionol sulfone, on 4 Salmonella typhimurium strains (TA97, TA98, TA100 and TA102) were investigated. Bithionol sulfoxide was found to be mutagenic to TA98 and TA100. However, mutagenicity was abolished in the presence of rat-liver S9 fractions. |
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