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Diameter of tumor blood vessels is a good parameter to estimate HIF-1-active regions in solid tumors
Authors:Harada Hiroshi  Xie Xuejun  Itasaka Satoshi  Zeng Lihua  Zhu Yuxi  Morinibu Akiyo  Shinomiya Kazumi  Hiraoka Masahiro
Institution:aDepartment of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606 8507, Japan;bNano-medicine Merger Education Unit, Kyoto University, Kyoto, Japan;cDepartment of Radiation Medicine, Fourth Military Medical University, Xi’an, China
Abstract:
Keywords:Hypoxia  Angiogenesis  Hypoxia-inducible factor-1 (HIF-1)  Vascular endothelial cell growth factor (VEGF)  Hypoxia-response element (HRE)  Tumor microenvironment  Optical imaging
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