Paralemnin of the lens |
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Authors: | Bagchi M Katar M Lo W-K Maisel H |
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Institution: | Department of Anatomy/Cell Biology, School of Medicine, Wayne State University, 540 East Canfield, Detroit, MI 48201, USA. |
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Abstract: | Paralemmin was identified in the chicken lens as a protein with mol. wt 65 kDa and a splice variant of 60 kDa, both soluble in Triton X-100. Paralemmin is localized to the plasma membrane of fiber cells, and was not detected in the annular pad cells. Thus in the chick lens it is another feature of fiber cell differentiation. Its localization to the short side of the fiber cell and the sites of fiber cell interlocking suggests that paralemmin may play a role in the development of such interdigitating processes. |
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Keywords: | lens paralemmin fiber cells |
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