Cucurbitane, hexanorcucurbitane and octanorcucurbitane glycosides from fruits of Trichosanthes tricuspidata. |
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| Authors: | Tripetch Kanchanapoom Ryoji Kasai Kazuo Yamasaki |
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| Institution: | Institute of Pharmaceutical Sciences, Faculty of Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan. |
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| Abstract: | From the fruits of Trichosanthes tricuspidata, 14 cucurbitane glycosides (khekadaengosides A-J, M-N, cucurbitacin J 2-O-beta-glucopyranoside and cucurbitacin K 2-O-beta-glucopyranoside), a hexanorcucurbitane glucoside (khekadaengoside K) and octanorcucurbitane (khekadaengoside L) were isolated along with two known cucurbitane glucosides (cucurbitacin 2-O-beta-glucopyranoside and 25-O-acetyl-cucurbitacin 2-O-beta-glucopyranoside). Structural elucidations were based on chemical and spectroscopic analyses. |
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| Keywords: | Trichosanthes tricupidata Cucurbitaceae Cucurbitane glycoside Hexanorcucurbitane glycoside Octanorcucurbitane glycoside Khekadaengosides A-N Khekadaengogenins I-V |
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