Alterations in surface hydrophobicity ofAcinetobacter baumannii induced by meropenem |
| |
Authors: | A Hoštacká |
| |
Institution: | (1) Institute of Preventive and Clinical Medicine, 833 01 Bratislava, Slovakia |
| |
Abstract: | Six strains ofAcinetobacter baumannii out of eleven strains tested revealed a strong hydrophobic character. This was demonstrated by adherence of bacteria to xylene
in the range of 90–94%. Changes in surface hydrophobicity of these strains were studied after treatment with meropenem at
subinhibitory concentrations (sub-MICs) (1/4, 1/8, 1/16 or 1/32 of the MICs). All strains showed a reduced adherence to xylene
after the action of meropenem at 1/4 or 1/16 of the MICs. Hydrophobicity of the treated bacteria was decreased to 1.3–70%
(1/16 of the MICs) or to 12–86% (1/4 of the MICs), depending on the strain. A decrease in surface hydrophobicity of three
strains was also observed after their exposure to meropenem at 1/8 of the MICs (to 18–71% of the control values). Meropenem
at 1/32 of the MICs practically did not affect bacterial hydrophobic properties, with the exception of one strain. |
| |
Keywords: | |
本文献已被 PubMed SpringerLink 等数据库收录! |
|