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Protective effect of orexin-A on 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y human dopaminergic neuroblastoma cells |
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| Authors: | Saeed Esmaeili-Mahani Somayeh Vazifekhah Hamzeh Pasban-Aliabadi Mehdi Abbasnejad Vahid Sheibani |
| Affiliation: | 1. Laboratory of Molecular Neuroscience, Kerman Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran;2. Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran |
| Abstract: | Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by progressive and selective death of midbrain dopaminergic neurons. Pharmacologic treatment of PD can be divided into symptomatic and neuroprotective therapies. |
| Keywords: | Orexin-A Parkinson&rsquo s disease 6-Hydroxydopamine Apoptosis SH-SY5Y cells |
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