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TRAIL‐Induced Caspase Activation Is a Prerequisite for Activation of the Endoplasmic Reticulum Stress‐Induced Signal Transduction Pathways
Authors:Dae‐Hee Lee  Ki Sa Sung  Zong Sheng Guo  William Taehyung Kwon  David L. Bartlett  Sang Cheul Oh  Yong Tae Kwon  Yong J. Lee
Affiliation:1. Department of Surgery, School of Medicine, University of Pittsburgh, Pittsburgh 15213, Pennsylvania;2. Division of Oncology/Hematology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea;3. Center for Pharmacogenetics and Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh 15261, Pennsylvania;4. Protein Metabolism Medical Research Center and Department of Biomedical Science, College of Medicine, Seoul National University, Seoul 110‐799, Korea;5. Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh 15213, Pennsylvania
Abstract:
Keywords:TRAIL‐INDUCED CASPASE‐8 ACTIVATION  TRAIL‐INDUCED ER STRESS  PERK‐eIF2α  ‐ATF4‐CHOP SIGNALS  CLEAVAGE OF BAP31
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