Molecular characterization and association analysis with production traits of the porcine <Emphasis Type="Italic">INPP5F</Emphasis> Gene |
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Authors: | Quan-Yong Zhou Jiang-Nan Huang Meng-Jin Zhu Shu-Hong Zhao |
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Institution: | (1) Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan, 430070, People’s Republic of China |
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Abstract: | Inositol polyphosphate-5-phosphatase F (INPP5F) is one of the largest families of phosphoinositide phosphatases, 5-phosphatase. It contains a Sac domain whose amino acids
are essential for inositol polyphosphate phosphatase activities. Here, we assigned the porcine INPP5F to SSC14q29 by using SCHP and IMpRH. Sequencing of PCR products from different breeds identified an A/G polymorphism in the
last exon. The allele frequencies of this SNP showed that the Yorkshire and Duroc pigs have high G allele frequency, whereas
the local pigs have high A allele frequency. Association analysis of the genotypes with growth and carcass traits found that
different genotypes of INPP5F have significant differences in average daily gain (ADG) (P < 0.05) in Yorkshire pigs. |
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Keywords: | Association analysis INPP5F Mapping Pig |
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