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Association of <Emphasis Type="Italic">Bordetella</Emphasis> dermonecrotic toxin with the extracellular matrix
Authors:Aya Fukui-Miyazaki  Shigeki Kamitani  Masami Miyake  Yasuhiko Horiguchi
Institution:(1) Department of Molecular Bacteriology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan;(2) Laboratory of Veterinary Public Health, Department of Veterinary Environmental Sciences, Osaka Prefecture University, Osaka, Japan
Abstract:

Background  

Bordetella dermonecrotic toxin (DNT) causes the turbinate atrophy in swine atrophic rhinitis, caused by a Bordetella bronchiseptica infection of pigs, by inhibiting osteoblastic differentiation. The toxin is not actively secreted from the bacteria, and is presumed to be present in only small amounts in infected areas. How such small amounts can affect target tissues is unknown.
Keywords:
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