Serotonin: A transmitter candidate in the vertebrate retina |
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| Authors: | N.N. Osborne T. Nesselhut D.A. Nicholas A.C. Cuello |
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| Affiliation: | Nuffield Laboratory of Ophthalmology and Dept. of Pharmacology and Human Anatomy, Oxford University, England |
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| Abstract: | It has been established by a combination of high performance liquid chromatographic and immunohistochemical methods that serotonin occurs in amacrine cell bodies and terminals situated in the inner plexiform layer of the frog retina, where enzymes for the synthesis of the same amine are also present. Potassium stimulation causes a release of previously accumulated radioactive serotonin by the retina. These findings support the opinion that serotonin is a retinal transmitter. |
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