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Letter: Preliminary crystallographic data for Escherichia coli beta-lactamase
Authors:J R Knox  P E Zorsky  N S Murthy
Institution:Biological Sciences Group and Institute of Material Sciences University of Connecticut Storrs, Conn. 06268, U.S.A.
Abstract:The β-lactamase (penicillinase) from Escherichia coli W3310 has been crystallized from 25% saturated ammonium sulfate solution at pH 6.9. An X-ray examination of the monoclinic crystals shows the space group is C2, with unit cell dimensions a = 47.2 A?, b = 76.9 A?, c = 73.3 A? and β = 98.6°. With Z = 4 and the molecular weight = 22,000 (Melling &; Scott, 1972), the Å3/dalton ratio is 2.98. The crystals are suitable for structure analysis to at least 2.4 Å resolution.
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