Hemodynamic response to LBNP during the 14 month MIR spaceflight (94-95)

Lower body negative pressure (LBNP) was used during the Mir spaceflight in a study of orthostatic tolerance. Hemodynamic responses were measured including heart rate, blood pressure, cerebral artery blood flow, and lower limb vascular resistance. Results showed that femoral flow volume decreased, which may be due to hypovolemia and reduced cardiac output. Additional changes in femoral vascular response and cerebral to femoral blood flow are discussed.