Monoclonal antibodies to antigens found on the neutrophils, activated T-lymphocytes and blast cells in human acute leukemia |
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Authors: | G Iu Miterev G F Burova M S Puzhitskaia S V Danilevich T I Bulycheva |
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Abstract: | Two hybridomas secreting mouse cytotoxic monoclonal antibodies to in vivo and in vitro activated human T-lymphocyte and neutrophil surface membrane antigenic determinants have been produced. One of these monoclonal antibodies (Ta/H-2) appeared to be also specifically reactive to blast cells in the majority of non-T-non-B and T acute lymphoblastic leukemia patients. |
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