Effect of malonate and maleate on growth and brefeldin a formation inCurvularia lunata |
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| Authors: | C T Sam |
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| Institution: | (1) Department of Pharmacy, University of Sydney, 2006 Sydney, New South Wales, Australia;(2) Present address: 2-V, Lorong Delima Sembilan, Island Glades, Penang, Malaysia |
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| Abstract: | Malonate exerted a stronger inhibitory effect on brefeldin A production than on mycelia growth in cultures ofCurvularia lunata especially at inhibitory levels of 100 to 200 mm. The extent of 200 mm malonate inhibition of growth and brefeldin A production
was greater in cultures treated with malonate prior to inoculation than those treated following 5 days after inoculation.
Maleate at levels of 40 to 220 mm activated brefeldin A formation in cultures though exerting variable effects on mycelia
growth. |
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