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Controlling organoid symmetry breaking uncovers an excitable system underlying human axial elongation
Institution:1. Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA;2. School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA;3. Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA;4. Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA;5. Broad Institute of MIT and Harvard, Cambridge, MA 02138, USA;6. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA 02138, USA
Abstract:
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  • Keywords:reproducible  human stem cell models  axial elongation  statistical inference  bioengineering
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