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Clonal replacement sustains long-lived germinal centers primed by respiratory viruses
Institution:1. Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA;2. Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA;3. Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA;4. Rutgers Robert Wood Johnson Medical School and Princeton University MD/PhD Program, Piscataway, NJ, USA;5. Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA;6. Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, USA;7. Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA, USA;8. Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA;9. Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Abstract:
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  • Keywords:Immunology  B cells  germinal centers  influenza  SARS-CoV-2  viruses  clonal dynamics
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