Genetic variation in the carbonic anhydrase isozymes of macaque monkeys. I. The radioimmunosorbent assay |
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Authors: | Erik Magid Joseph DeSimone Richard E. Tashian |
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Affiliation: | (1) Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan;(2) Present address: Department of Clinical Chemistry, Bispebjerg Hospital, Bispebjerg Bakke 23, 2400 Copenhagen NV, Denmark |
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Abstract: | A radioimmunosorbent technique is described which is capable of independently detecting both isozymes of carbonic anhydrase, CA I and CA II, in concentrations as low as 1 ng/ml. The technique is used to quantitate the different electrophoretic variants of red cell CA I as well as levels of CA II in the pig-tailed macaque, Macaca nemestrina.Supported by U.S. Public Health Service research grant GM-15419.U.S. Public Health Service Predoctoral Trainee (GM-71-14). |
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