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Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover |
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| Affiliation: | 1. UCL Cancer Institute, University College London, London WC1E 6DD, UK;2. MRC Laboratory for Molecular Biology, University College London, London WC1E 6BS, UK;3. Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin 13125, Germany;4. MRC Laboratory of Molecular Cell Biology, University of Cambridge, Cambridge CB2 0QH, UK;5. Faculty of Biology, Chemistry, and Pharmacy, Freie Universität Berlin, Berlin 14195, Germany |
| Abstract: |  |
| Keywords: | phosphoinositide phosphatidylinositol-3,4-bisphosphate class II PI3K focal adhesion cell migration RhoA signaling ARAP3 PKN2 DEPDC1B lipid switch |
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