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Klf5 defines alveolar epithelial type 1 cell lineage commitment during lung development and regeneration
Affiliation:1. Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA;2. Penn Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104, USA;3. Penn-CHOP Lung Biology Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA;4. Institute for Regenerative Medicine, University of Pennsylvania, Perelman School of Medicine Philadelphia, PA 19104, USA;5. Department of Electrical Engineering and Computer Sciences, UC Berkeley, Berkeley, CA 94720, USA;6. Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA;7. Medical Scientist Training Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Abstract:
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  • Keywords:Klf5  alveolar epithelial cells  cell fate  lung development  lung regeneration  influenza  hyperoxia  organoid
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