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Predominant localization of dihydroxyacetone-phosphate acyltransferase activity in renal peroxisomes of male and female mice
Authors:M I Mackness  M J Connock
Abstract:The subcellular localization of DHAPAT activity in male and female albino mouse kidneys was investigated by density gradient centrifugation. DHAPAT has a predominantly peroxisomal distribution in both male and female kidneys; however some activity is also distributed in a less dense region of the gradient, predominantly containing microsomes. Peroxisomal fractions also contain some lactate dehydrogenase activity and approximately 9% of the cellular NAD-dependent alpha-glycerophosphate dehydrogenase activity.
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