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Genome-wide CRISPR activation screen identifies candidate receptors for SARS-CoV-2 entry |
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| Authors: | Zhu Shiyou Liu Ying Zhou Zhuo Zhang Zhiying Xiao Xia Liu Zhiheng Chen Ang Dong Xiaojing Tian Feng Chen Shihua Xu Yiyuan Wang Chunhui Li Qiheng Niu Xuran Pan Qian Du Shuo Xiao Junyu Wang Jianwei Wei Wensheng |
| Affiliation: | 1.Biomedical Pioneering Innovation Center, Beijing Advanced Innovation Center for Genomics, Peking-Tsinghua Center for Life Sciences, Peking University Genome Editing Research Center, State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, 100871, China ;2.State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, 100871, China ;3.Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, 100871, China ;4.Beijing Advanced Innovation Center for Genomics, Peking University, Beijing, 100871, China ;5.NHC Key Laboratory of Systems Biology of Pathogens and Christophe Merieux Laboratory, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China ;6.Key Laboratory of Respiratory Disease Pathogenomics, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China ;7.Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, 100871, China ; |
| Abstract: | Science China Life Sciences - The outbreak of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has created a global health crisis. SARS-CoV-2 infects varieties of tissues where the known... |
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