Zeamatin inhibits trypsin and alpha-amylase activities |
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| Authors: | Schimoler-O'Rourke R Richardson M Selitrennikoff C P |
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| Institution: | Mycologics, Inc., Denver, CO 80262, USA. |
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| Abstract: | Zeamatin is a 22-kDa protein isolated from Zea mays that has antifungal activity against human and plant pathogens. Unlike other pathogenesis-related group 5 proteins, zeamatin inhibits insect alpha-amylase and mammalian trypsin activities. It is of clinical significance that zeamatin did not inhibit human alpha-amylase activity and inhibited mammalian trypsin activity only at high molar concentrations. |
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