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Synthesis and Biological Activity of Analogs of the Cecropia Juvenile Hormone with Different Alkyl Substituents at C-7 and C-11
Authors:Yoichi Ozawa  Kenji Mori  Masanao Matsui
Institution:Central Research Laboratories, Ajinomoto Co., Inc., Kawasaki-shi, Kanagawa 210
Abstract:Sixteen new Cecropia juvenile hormone (JH) analogs with different alkyl substituents at C–7 and C–11 were synthesized as stereoisomeric mixtures. The epoxides with n-propyl or n-butyl and methyl groups at C-11 and methyl or ethyl group at C-7 showed high JH activity on Bombyx mori L. Structure-activity relationship of the JH analogs was discussed.
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